Asociación entre enfermedad periodontal y parto pretérmino en un grupo de mujeres puérperas del norte de México / Association between periodontal disease and preterm birth in a group of puerperal women from northern of Mexico

Introducción: La enfermedad periodontal puede ser causa de lesiones sistémicas. Se conoce la prevalencia de enfermedad periodontal en mayores de 35 años y el aumento de los factores de riesgo en mujeres embarazadas, pero no se sabe si estos factores se potencializan en mujeres embarazadas menores de 35 años. En México son muy prevalentes tanto el embarazo en mujeres jóvenes como el parto pretérmino. Con el objetivo de conocer la prevalencia de la enfermedad periodontal y su asociación con el parto prematuro, se realizó este estudio en mujeres puérperas menores de 35 años en una población abierta. Material y métodos: Estudio de tipo observacional, descriptivo y transversal, analizando casos y controles. La población de estudio fueron pacientes puérperas entre 17 y 35 años que ingresaron a un hospital público durante parte del año 2019. Se utilizó el índice de necesidad de tratamiento periodontal en la comunidad (CPITN, por sus siglas en inglés) para la medición de enfermedad periodontal (EP), se consideró embarazo prematuro (PP) cuando el parto ocurrió con menos de 37 semanas de embarazo. Como covariables se consideraron edad, tabaquismo y paridad. Se buscó la asociación mediante regresión logística para el cálculo de la razón de momios. Resultados: Se analizaron 323 mujeres, 200 (62%) tuvieron niveles 3 y 4 CPITN; 10.8% (35) tuvieron parto prematuro, la razón de momios cruda para la asociación entre código CPITN 3 y 4 y parto prematuro fue de 3.3 (p < 0.01). Después de ajustar por otros predictores la asociación se mantuvo en 3.8 (p < 0.01). Conclusiones: Es la primera vez en nuestro medio que se encuentra esta asociación entre enfermedad periodontal y parto prematuro. La prevalencia de parto prematuro en este grupo fue más alta que la media nacional. Es necesaria la revisión odontológica durante las visitas prenatales. Debe continuarse la línea de investigación con un estudio prospectivo (AU)

Introduction: Periodontal disease can cause systemic injuries. Prevalence of periodontal disease in people older than 35 years old is known, as well as the risk factors for pregnant women; however, it is not known if these factors also apply for pregnant women younger than 35 years of age. In Mexico, pregnancy among young women and preterm birth are very prevalent. The present study was done with the objective of finding out the prevalence of periodontal disease and its relationship with preterm birth in puerperal women younger than 35 years old in a population without social security. Material and methods: The study is observational, descriptive and transversal, analysis type cases and controls was done. The population for the study consists on puerperal patients between the ages of 17 to 35 years, all of them were admitted into a public hospital in a period of 2019. The Community Periodontal Index of Treatment Need (CPITN) was used to measure periodontal disease in the patients. Preterm birth was defined as a birth occur before 37 weeks of pregnancy. Age, smoking and parity were used as covariables. Logistic regression was used to evaluate the association between periodontal disease and preterm birth through odds ratio values. Results: 323 women were analyzed, 200 (62%) had levels of 3 and 4 on the CPITN. 10.8% (35) had preterm birth, the raw odds ratio for the association between the codes 3 and 4 from the CPITN was of 3.3 (p < 0.01), after adjusting other predictors the association was 3.8 (remaining as a p < 0.01). Conclusions: It is the first time that such an association between periodontal disease and preterm birth has been found in the region. Prevalence of preterm birth in the group studied was higher than the national's average. An odontological revision during prenatal visits is needed. This line of research should be continued through a prospective study (AU)

Prevalence of Rheumatic Diseases and Quality of Life in the Saraguro Indigenous People, Ecuador: A Cross-sectional Community-Based Study.

Rheumatic diseases are more prevalent and aggressive in indigenous population groups, providing medical attention for which poses a challenge for the rheumatologist. OBJECTIVE: To estimate the prevalence of musculoskeletal (MSK) disorders and rheumatic diseases in the Saraguro indigenous people in Ecuador, as well as to identify the main factors associated with the health status of this population. METHODS: This observational, cross-sectional study focused on the community was conducted using the COPCORD (Community-Oriented Program for Control of Rheumatic Diseases) methodology. The required data were obtained using the following instruments: (1) a screening for MSK disorders and rheumatic diseases; (2) a sociodemographic questionnaire; (3) a functional capacity Health Assessment Questionnaire Disability Index questionnaire; and (4) the quality of life EQ-5D-3L (EuroQoL) questionnaire. The rheumatologists working with the indigenous community were responsible for examining and treating study participants suffering from MSK disorders. RESULTS: The study sample comprised 2687 individuals, with mean age of 44 (SD, 19.9) years, 1690 (62.9%) of whom were women; Kichwa speakers comprised 32.4% (872), and 1244 (46.3%) reported MSK pain. The most prevalent conditions were as follows: low back pain (9.3%), hand osteoarthritis (OA, 7.2%), knee OA (6.5%), rheumatic regional pain syndrome (5.8%), fibromyalgia (1.8%), and rheumatoid arthritis (1.3%). Lower education level, unemployment, cooking with firewood, and rheumatic diseases were associated with a lower quality of life. CONCLUSIONS: Musculoskeletal disorders, rheumatic diseases, and rheumatoid arthritis were found to be highly prevalent in the studied population. Rheumatoid arthritis and hand OA had the most significant impact on the quality of life.

Lung cancer mortality and radon concentration in a chronically exposed neighborhood in Chihuahua, Mexico: a geospatial analysis.

This study correlated lung cancer (LC) mortality with statistical data obtained from government public databases. In order to asses a relationship between LC deaths and radon accumulation in dwellings, indoor radon concentrations were measured with passive detectors randomly distributed in Chihuahua City. Kriging (K) and Inverse-Distance Weighting (IDW) spatial interpolations were carried out. Deaths were georeferenced and Moran's I correlation coefficients were calculated. The mean values (over n = 171) of the interpolation of radon concentrations of deceased's dwellings were 247.8 and 217.1 Bq/m(3), for K and IDW, respectively. Through the Moran's I values obtained, correspondingly equal to 0.56 and 0.61, it was evident that LC mortality was directly associated with locations with high levels of radon, considering a stable population for more than 25 years, suggesting spatial clustering of LC deaths due to indoor radon concentrations.

Algunos efectos reproductivos y sistémicos en ratas macho expuestas a Paratión Metílico: un aporte a la evaluación de riesgo / Some reproductive and systemic effects on male rats exposed to methyl parathion: a contribution to risk assessment

Con el fin de contribuir a dilucidar la controversia existente con relación a la asociación entre efectos reproductivos adversos y exposición a plaguicidas órgano fosforados, se realizó el presente estudio. Mediante un diseño experimental se trataron 79 ratas machos durante 90 días, con Paratión Metílico® vía oral, con diferentes dosis (0.0, 1.0, 1.5 y 2.0 mg/kg/día). La mitad del grupo con dieta ad libitum y la mitad con dieta restringida al 75 por cento. Se midieron como efectos reproductivos: motilidad del espermatozoide y peso de testículos y epidídimo y, sistémicos: peso del animal y visceral. Se estimaron las dosis de referencia (DRf), con la metodología de Análisis de Riesgo de la Agencia de Protección del Medio Ambiente de Estados Unidos (EPA). La motilidad del espermatozoide (<30 por cento), se afectó significativamente (p < 0.02) debido a la dieta. Con la exposición al plaguicida se obtuvieron OR de 2.4, 3.5, y 5.6 conforme aumentó la dosis (p<0.01). El peso de los testículos e hígado arrojó diferencias significativas (p<0.01) con efecto dosis-respuesta para Paratión Metílico. Se consideran valores críticos y se recomiendan dosis de refenerecia para exposición humana, para motilidad del espermatozoide DRf=2x10-4 y peso corporal DRf=1x10-2, entre otros. La asociación observada en este trabajo apoya la hipótesis de que la función reproductiva puede verse afectada por la exposición a Paratión Metílico

Effect of maternal bone lead on length and head circumference of newborns and 1-month-old infants.

The authors evaluated the effects that maternal bone lead stores have in anthropometry at birth in 223 mother-infant pairs. The participants were recruited between April and November 1994. Anthropometric data were collected within the first 12 hr following delivery. Maternal information was obtained 1 mo after delivery occurred. Bone lead burden was determined with in-vivo K-x-ray fluorescence of the tibia (cortical bone) and the patella (trabecular bone). The authors transformed anthropometric measurements to an ordinal 5-category scale, and the association of measurements with other factors was evaluated with ordinal logistic-regression models. Mean bone lead levels were 9.8 microgram/gm bone mineral and 14.4 microgram/gm bone mineral for the tibia and patella, respectively. Birth length of newborns decreased as tibia lead levels increased. Compared with women in the lower quintiles of the distribution of tibia lead, those in the upper quintile had a 79% increase in risk of having a lower birth length newborn (odds ratio = 1.79; 95% confidence interval = 1.10, 3.22). The authors adjusted by birth weight, and the effect was attenuated--but nonetheless significant. Patella lead was positively and significantly related to the risk of a low head circumference score; this score remained unaffected by inclusion of birth weight. The authors estimated the increased risk to be 1.02 per microgram lead/gm bone mineral (95% confidence interval = 1.01, 1.04 per microgram lead/gm bone mineral). Odds ratios did not vary substantially after the authors adjusted for birth weight and other important determinants of head circumference.